POLE 抗体 (AA 1230-1310)
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北京 101111
Quick Overview for POLE 抗体 (AA 1230-1310) (ABIN7223256)
抗原
See all POLE 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1230-1310
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原理
- Rabbit Anti-DNA pol ε A Polyclonal Antibody
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特异性
- DNA pol ε A Polyclonal Antibody detects endogenous levels of DNA pol ε A protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human DNA pol epsilon A at AA range: 1230-1310
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亚型
- IgG
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anti-Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE) (AA 1-370) antibody
POLE 适用: 人 IF, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE) (AA 1175-1311), (Catalytic Subunit) antibodyPOLE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE) (AA 101-200) antibodyPOLE 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE) (AA 1-370) antibodyPOLE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- POLE (Polymerase (DNA Directed), Epsilon, Catalytic Subunit (POLE))
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别名
- DNA pol epsilon A
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背景
- POLE, POLE1, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit APOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.
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基因ID
- 5426
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UniProt
- Q07864
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途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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