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PKD2 抗体 (pSer812)

This 兔 多克隆 anti-PKD2 antibody specifically detects PKD2 in ELISA 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7223162
发货至: 中国
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Quick Overview for PKD2 抗体 (pSer812) (ABIN7223162)

抗原

See all PKD2 抗体
PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

适用

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人, 小鼠, 大鼠

宿主

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  • 1

克隆类型

  • 72
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多克隆

标记

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This PKD2 antibody is un-conjugated

应用范围

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ELISA, Immunofluorescence (IF)
  • 抗原表位

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    pSer812

    原理

    PKD2 (phospho Ser812) Polyclonal Antibody

    特异性

    Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PKD2 Phospho-Ser812

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

    别名

    PKD2

    背景

    Rabbit Anti-PKD2 (phospho Ser812) Polyclonal Antibody,PKD2, Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321,PKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in PKD2 are associated with autosomal dominant polycystic kidney disease type 2.,Polycystin-2

    基因ID

    5311

    UniProt

    Q13563

    途径

    cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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