PKD2 抗体 (pSer812)
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北京 101111
Quick Overview for PKD2 抗体 (pSer812) (ABIN7223162)
抗原
See all PKD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer812
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原理
- PKD2 (phospho Ser812) Polyclonal Antibody
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特异性
- Phospho-PKD2 (S812) Polyclonal Antibody detects endogenous levels of PKD2S812.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human PKD2 Phospho-Ser812
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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别名
- PKD2
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背景
- Rabbit Anti-PKD2 (phospho Ser812) Polyclonal Antibody,PKD2, Polycystin-2, Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystwin, R48321,PKD2 (polycystin 2, transient receptor potential cation channel) encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in PKD2 are associated with autosomal dominant polycystic kidney disease type 2.,Polycystin-2
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基因ID
- 5311
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UniProt
- Q13563
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途径
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
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