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PDGFRA 抗体

PDGFRA 适用: 人, 小鼠, 大鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 7A3 unconjugated
产品编号 ABIN7212300
发货至: 中国
  • 抗原 See all PDGFRA 抗体
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    适用
    • 237
    • 125
    • 70
    • 19
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 214
    • 38
    • 4
    • 1
    小鼠
    克隆类型
    • 207
    • 50
    单克隆
    标记
    • 110
    • 20
    • 18
    • 14
    • 14
    • 11
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    This PDGFRA antibody is un-conjugated
    应用范围
    • 171
    • 108
    • 65
    • 54
    • 54
    • 40
    • 34
    • 22
    • 22
    • 14
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    原理
    PDGFRα Mouse Monoclonal Antibody (7A3)
    特异性
    PDGFRα protein detects endogenous levels of PDGFRA.
    纯化方法
    The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
    免疫原
    Synthetic Peptide of PDGFRalpha at AA range of 1010-1090
    克隆位点
    7A3
    亚型
    IgG1
    Top Product
    Discover our top product PDGFRA Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
    说明

    Primary Antibody

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    别名
    PDGFRalpha (PDGFRA 产品)
    别名
    AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
    背景
    Mouse Anti-PDGFRα Mouse Monoclonal Antibody (7A3),PDGFRA,PDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that PDGFRA plays a role in organ development, wound healing, and tumor progression. Mutations in PDGFRA have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.,PDGFRA
    分子量
    observerd band 180kDa
    基因ID
    5156
    UniProt
    P16234
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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