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PDGFRA 抗体 (pTyr754)

The 兔 多克隆 anti-PDGFRA antibody is suitable to detect PDGFRA in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7223044
发货至: 中国
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Quick Overview for PDGFRA 抗体 (pTyr754) (ABIN7223044)

抗原

See all PDGFRA 抗体
PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PDGFRA antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pTyr754

    原理

    PDGFR-α (phospho Tyr754) Polyclonal Antibody

    特异性

    Phospho-PDGFR-α (Y754) Polyclonal Antibody detects endogenous levels of PDGFR-α protein only when phosphorylated at Y754.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human PDGFR-alpha Phospho-Tyr754

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

    别名

    PDGFR-alpha

    背景

    Rabbit Anti-PDGFR-α (phospho Tyr754) Polyclonal Antibody,PDGFRA, PDGFR2, RHEPDGFRA, Platelet-derived growth factor receptor alpha, PDGF-R-alpha, PDGFR-alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD14,PDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in PDGFRA have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.,Platelet-derived growth factor receptor alpha

    分子量

    observerd band 122kDa

    基因ID

    5156

    UniProt

    P16234

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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