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PLAU 抗体 (Internal Region)

The 兔 多克隆 anti-PLAU antibody (ABIN7223172) specifically detects PLAU in ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7223172
发货至: 中国
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Quick Overview for PLAU 抗体 (Internal Region) (ABIN7223172)

抗原

See all PLAU 抗体
PLAU (Plasminogen Activator, Urokinase (PLAU))

适用

  • 96
  • 35
  • 29
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宿主

  • 88
  • 14
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克隆类型

  • 83
  • 35
  • 2
多克隆

标记

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This PLAU antibody is un-conjugated

应用范围

  • 82
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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
    • 6
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    Internal Region

    原理

    uPA Polyclonal Antibody

    特异性

    UPA Polyclonal Antibody detects endogenous levels of uPA protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human uPA

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PLAU (Plasminogen Activator, Urokinase (PLAU))

    别名

    uPA

    背景

    Rabbit Anti-uPA Polyclonal Antibody,PLAU, Urokinase-type plasminogen activator, U-plasminogen activator, uPA,PLAU (plasminogen activator, urokinase) encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in PLAU may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Urokinase-type plasminogen activator

    基因ID

    5328

    UniProt

    P00749

    途径

    Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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