PHKB 抗体 (AA 630-710)
Quick Overview for PHKB 抗体 (AA 630-710) (ABIN7223140)
抗原
See all PHKB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 630-710
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原理
- PHKB Polyclonal Antibody
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特异性
- PHKB Polyclonal Antibody detects endogenous levels of PHKB protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human PHKB at AA range: 630-710
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亚型
- IgG
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anti-Phosphorylase Kinase, beta (PHKB) (AA 854-1093), (Regulatory Subunit) antibody
PHKB 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphorylase Kinase, beta (PHKB) (Internal Region) antibodyPHKB 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphorylase Kinase, beta (PHKB) (AA 854-1093) antibodyPHKB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphorylase Kinase, beta (PHKB) (AA 984-1093) antibodyPHKB 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Phosphorylase Kinase, beta (PHKB) antibodyPHKB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Phosphorylase Kinase, beta (PHKB) (AA 984-1093) antibodyPHKB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E9 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PHKB (Phosphorylase Kinase, beta (PHKB))
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别名
- PHKB
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背景
- Rabbit Anti-PHKB Polyclonal Antibody,PHKB, Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta,Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by PHKB (phosphorylase kinase regulatory subunit beta), which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in PHKB cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.,Phosphorylase b kinase regulatory subunit beta
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分子量
- observerd band 124kDa
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基因ID
- 5257
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UniProt
- Q93100
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途径
- Cellular Glucan Metabolic Process
抗原
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