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PHKB 抗体

PHKB 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7264075
发货至: 中国
  • 抗原 See all PHKB 抗体
    PHKB (Phosphorylase Kinase, beta (PHKB))
    适用
    • 28
    • 7
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 25
    • 3
    • 2
    克隆类型
    • 28
    • 2
    多克隆
    标记
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PHKB antibody is un-conjugated
    应用范围
    • 29
    • 13
    • 13
    • 12
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human PHKB (NP_000284.1).
    亚型
    IgG
    Top Product
    Discover our top product PHKB Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PHKB (Phosphorylase Kinase, beta (PHKB))
    别名
    PHKB (PHKB 产品)
    别名
    AI463271 antibody, phosphorylase kinase regulatory subunit beta antibody, phosphorylase kinase beta antibody, PHKB antibody, Phkb antibody
    背景
    Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.
    分子量

    Observed_MW: 125 kDa

    Calculated_MW: 123 kDa/124 kDa

    基因ID
    5257
    UniProt
    Q93100
    途径
    Cellular Glucan Metabolic Process
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