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PDE5A 抗体

This anti-PDE5A antibody is a 兔 多克隆 antibody detecting PDE5A in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7230560
发货至: 中国

Quick Overview for PDE5A 抗体 (ABIN7230560)

抗原

See all PDE5A 抗体
PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PDE5A antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 原理

    PDE5A Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of PDE5A protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human PDE5A protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

    别名

    PDE5A

    背景

    Rabbit Anti-PDE5A Polyclonal Antibody,cGMP-specific 3',5'-cyclic phosphodiesterase, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE,PDE5A (Phosphodiesterase 5A) is a Protein Coding gene. Diseases associated with PDE5A include Priapism and Nonarteritic Anterior Ischemic Optic Neuropathy. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Platelet homeostasis. PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of PDE5A results in three transcript variants encoding distinct isoforms.,PDE5A

    分子量

    observerd band 96kDa

    基因ID

    8654

    UniProt

    O76074

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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