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PDE5A 抗体 (C-Term)

PDE5A 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789423
发货至: 中国
  • 抗原 See all PDE5A 抗体
    PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
    抗原表位
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼
    宿主
    • 24
    • 3
    • 1
    克隆类型
    • 26
    • 2
    多克隆
    标记
    • 18
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE5A antibody is un-conjugated
    应用范围
    • 19
    • 15
    • 11
    • 9
    • 8
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
    产品特性
    This is a rabbit polyclonal antibody against PDE5A. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product PDE5A Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 823 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ioki, Wu, Takayama, Motohashi, Wakai, Funahashi: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." in: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).

  • 抗原
    PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
    别名
    PDE5A (PDE5A 产品)
    背景
    This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
    Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1
    Protein Interaction Partner: UBC, PRKG1, CASP3,
    Protein Size: 823
    分子量
    93 kDa
    基因ID
    8654
    NCBI登录号
    NM_033437, NP_246273
    UniProt
    O76074
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling
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