PDE5A 抗体 (C-Term)
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北京 101111
Quick Overview for PDE5A 抗体 (C-Term) (ABIN2789423)
抗原
See all PDE5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- PDE5A Antibody - C-terminal region
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序列
- TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
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产品特性
- This is a rabbit polyclonal antibody against PDE5A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) antibody
Verified PDE5A 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (AA 29-138) antibodyPDE5A 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 9H5 unconjugated
anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (C-Term) antibodyPDE5A 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (AA 101-200) antibodyPDE5A 适用: 人 WB, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (AA 1-150) antibodyPDE5A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 5A, cGMP-Specific (PDE5A) (N-Term) antibodyPDE5A 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63250-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." in: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).
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- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
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别名
- PDE5A
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背景
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Background Information: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Gene Name: Phosphodiesterase 5A, cGMP-specific
Alternative Symbols: CN5A, PDE5, CGB-PDE
Protein Name: cGMP-specific 3',5'-cyclic phosphodiesterase
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分子量
- 93kDa
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基因ID
- 8654
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NCBI登录号
- NP_246273
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UniProt
- O76074
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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