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Perforin 1 抗体 (AA 451-500)

This 兔 多克隆 anti-Perforin 1 antibody specifically detects Perforin 1 in WB 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7226902
发货至: 中国
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Quick Overview for Perforin 1 抗体 (AA 451-500) (ABIN7226902)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Perforin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 451-500

    原理

    Perforin 1 Polyclonal Antibody

    特异性

    Perforin 1 Polyclonal Antibody detects endogenous levels of Perforin 1.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from Perforin 1 at AA range: 451-500

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    Perforin 1

    背景

    Rabbit Anti-Perforin 1 Polyclonal Antibody,Perforin-1, P1, Cytolysin, Lymphocyte pore-forming protein, PFP,The protein encoded by PRF1 (perforin 1) has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.,Perforin 1

    分子量

    observerd band 61kDa

    基因ID

    5551

    UniProt

    P14222

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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