OTUB1 抗体 (AA 20-100)
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Quick Overview for OTUB1 抗体 (AA 20-100) (ABIN7226620)
抗原
See all OTUB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-100
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原理
- Otubain-1 Polyclonal Antibody
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特异性
- Otubain-1 Polyclonal Antibody detects endogenous levels of Otubain-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Otubain-1 at AA range: 20-100
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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别名
- Otubain-1
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背景
- Rabbit Anti-Otubain-1 Polyclonal Antibody,OTUB1, OTB1, OTU1, HSPC263, Ubiquitin thioesterase OTUB1, Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, hOTU1, Ubiquitin-specific-processing protease OTUB1,The product of OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.,Ubiquitin thioesterase OTUB1
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分子量
- observerd band 31kDa
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基因ID
- 55611
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UniProt
- Q96FW1
抗原
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