OPN4 抗体 (AA 400-480)
Quick Overview for OPN4 抗体 (AA 400-480) (ABIN7215736)
抗原
See all OPN4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-480
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原理
- Melanopsin Polyclonal Antibody
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特异性
- Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human Melanopsin at AA range: 400-480
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亚型
- IgG
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anti-Opsin 4 (OPN4) (C-Term) antibody
OPN4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Opsin 4 (OPN4) (C-Term) antibodyOPN4 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Opsin 4 (OPN4) (AA 429-478) antibodyOPN4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- OPN4 (Opsin 4 (OPN4))
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别名
- Melanopsin
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背景
- Rabbit Anti-Melanopsin Polyclonal Antibody,OPN4, MOP, Melanopsin, Opsin-4,Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. OPN4 encodes a photoreceptive opsin protein melanopsin that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. Melanopsin functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms.,Melanopsin
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分子量
- observerd band 55kDa
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基因ID
- 94233
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UniProt
- Q9UHM6
抗原
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