OPN4 抗体 (AA 429-478)
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北京 101111
Quick Overview for OPN4 抗体 (AA 429-478) (ABIN1535846)
抗原
See all OPN4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 429-478
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原理
- Melanopsin Antibody
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特异性
- Melanopsin Polyclonal Antibody detects endogenous levels of Melanopsin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human OPN4. AA range:429-478
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亚型
- IgG
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anti-Opsin 4 (OPN4) (AA 400-480) antibody
OPN4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Opsin 4 (OPN4) (C-Term) antibodyOPN4 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Opsin 4 (OPN4) (C-Term) antibodyOPN4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- OPN4 (Opsin 4 (OPN4))
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别名
- OPN4
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背景
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Synonyms: OPN4, MOP, Melanopsin, Opsin-4
Background: Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily.This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by Ref
Gene Name: OPN4
Protein Name: Melanopsin
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分子量
- 52 kDa
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基因ID
- 94233
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OMIM
- 606665
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UniProt
- Q9UHM6
抗原
-
