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OPRK1 抗体 (AA 290-370)

This 兔 多克隆 anti-OPRK1 antibody specifically detects OPRK1 in WB 和 ELISA. The antibody is reactive with 人, 大鼠, 小鼠 和 猴 samples.
产品编号 ABIN7222868
发货至: 中国
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Quick Overview for OPRK1 抗体 (AA 290-370) (ABIN7222868)

抗原

See all OPRK1 抗体
OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

适用

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人, 大鼠, 小鼠, 猴

宿主

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  • 2
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克隆类型

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  • 11
多克隆

标记

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This OPRK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 290-370

    原理

    KOR-1 Polyclonal Antibody

    特异性

    KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human KOR-1 at AA range: 290-370

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

    别名

    KOR-1

    背景

    Rabbit Anti-KOR-1 Polyclonal Antibody,OPRK1, OPRK, Kappa-type opioid receptor, K-OR-1, KOR-1,OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.,Kappa-type opioid receptor

    分子量

    observerd band 48kDa

    基因ID

    4986

    UniProt

    P41145
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