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OPRK1 抗体 (N-Term)

OPRK1 适用: 人, 大鼠, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6257760
发货至: 中国
  • 抗原 See all OPRK1 抗体
    OPRK1 (Opioid Receptor, kappa 1 (OPRK1))
    抗原表位
    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 47
    • 44
    • 38
    • 3
    • 2
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 61
    • 3
    • 1
    克隆类型
    • 63
    • 2
    多克隆
    标记
    • 36
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OPRK1 antibody is un-conjugated
    应用范围
    • 41
    • 26
    • 12
    • 11
    • 11
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    OPRK1 Antibody detects endogenous levels of total OPRK1.
    预测反应
    Bovine,Horse
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human OPRK1, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product OPRK1 Primary Antibody
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    OPRK1 (Opioid Receptor, kappa 1 (OPRK1))
    别名
    OPRK1 (OPRK1 产品)
    别名
    OPRK1 antibody, LOC780448 antibody, kor antibody, KOR antibody, OPRK antibody, K-OR-1 antibody, KOR-1 antibody, MSL-1 antibody, Oprk2 antibody, R21 antibody, opioid receptor, kappa 1 antibody, opioid receptor kappa 1 antibody, oprk1 antibody, OPRK1 antibody, Oprk1 antibody
    背景

    Description: G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

    Gene: OPRK1

    分子量
    48 kDa
    基因ID
    4986
    UniProt
    P41145
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