NKX2-8 抗体 (AA 10-90)
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北京 101111
Quick Overview for NKX2-8 抗体 (AA 10-90) (ABIN7220988)
抗原
See all NKX2-8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- Nkx-2.8 Polyclonal Antibody
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特异性
- Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human Nkx-2.8 at AA range: 10-90
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
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别名
- Nkx-2.8
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背景
- Rabbit Anti-Nkx-2.8 Polyclonal Antibody,The NK2 homeobox 8 encoded by NKX2-8 is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.,Homeobox protein Nkx-2.8
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分子量
- observerd band 26kDa
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基因ID
- 26257
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UniProt
- Q8IUT7
抗原
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