Neurofibromin 1 抗体 (AA 1520-1600)
Quick Overview for Neurofibromin 1 抗体 (AA 1520-1600) (ABIN7216026)
抗原
See all Neurofibromin 1 (NF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1520-1600
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原理
- Neurofibromin Polyclonal Antibody
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特异性
- Neurofibromin Polyclonal Antibody detects endogenous levels of Neurofibromin protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Neurofibromin at AA range: 1520-1600
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Neurofibromin 1 (NF1)
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别名
- Neurofibromin
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背景
- Rabbit Anti-Neurofibromin Polyclonal Antibody,NF1, Neurofibromin, Neurofibromatosis-related protein NF-1,NF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.,Neurofibromin
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分子量
- observerd band 319kDa
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基因ID
- 4763
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UniProt
- P21359
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途径
- cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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