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NACA 抗体 (pSer43)

This anti-NACA antibody is a 兔 多克隆 antibody detecting NACA in ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7222642
发货至: 中国

Quick Overview for NACA 抗体 (pSer43) (ABIN7222642)

抗原

See all NACA (NACa1) 抗体
NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

适用

人, 小鼠, 大鼠

宿主

  • 9
  • 2

克隆类型

  • 11
多克隆

标记

  • 11
This NACA antibody is un-conjugated

应用范围

  • 8
  • 5
  • 5
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    pSer43

    原理

    NACA (phospho Ser43) Polyclonal Antibody

    特异性

    Phospho-NACA (S43) Polyclonal Antibody detects endogenous levels of NACA protein only when phosphorylated at S43.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human NACA Phospho-Ser43

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))

    别名

    NACA

    背景

    Rabbit Anti-NACA (phospho Ser43) Polyclonal Antibody,NACA, HSD48, Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, allergen Hom s 2,NACA encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of NACA on different chromosomes.,Nascent polypeptide-associated complex subunit alpha

    基因ID

    4666

    UniProt

    Q13765

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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