NACA 抗体 (pSer43)
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北京 101111
Quick Overview for NACA 抗体 (pSer43) (ABIN1450497)
抗原
See all NACA (NACa1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-58, pSer43
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原理
- NACA (phospho Ser43) Antibody
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特异性
- Phospho-NACA (S43) Polyclonal Antibody detects endogenous levels of NACA protein only when phosphorylated at S43.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- The antiserum was produced against synthesized peptide derived from human NACA around the phosphorylation site of Ser43. AA range:9-58
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亚型
- IgG
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anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) (AA 1-215) antibody
NACa1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) (C-Term) antibodyNACa1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nascent Polypeptide Associated Complex alpha 1 (NACa1) (AA 1-215) antibodyNACa1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- NACA (NACa1) (Nascent Polypeptide Associated Complex alpha 1 (NACa1))
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别名
- NACA
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背景
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Synonyms: NACA, HSD48, Nascent polypeptide-associated complex subunit alpha, NAC-alpha, Alpha-NAC, allergen Hom s 2
Background: This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016],
Gene Name: NACA
Protein Name: Nascent polypeptide-associated complex subunit alpha
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分子量
- 23 kDa
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基因ID
- 4666
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OMIM
- 601234
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UniProt
- Q13765
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
-
