MLH3 抗体 (AA 490-570)
Quick Overview for MLH3 抗体 (AA 490-570) (ABIN7221088)
抗原
See all MLH3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 490-570
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原理
- MLH3 Polyclonal Antibody
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特异性
- MLH3 Polyclonal Antibody detects endogenous levels of MLH3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human MLH3 at AA range: 490-570
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亚型
- IgG
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anti-MutL Homolog 3 (MLH3) (Internal Region) antibody
MLH3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (C-Term) antibodyVerified MLH3 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) antibodyMLH3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (AA 1188-1237) antibodyMLH3 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-MutL Homolog 3 (MLH3) (AA 521-570) antibodyMLH3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MLH3 (MutL Homolog 3 (MLH3))
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别名
- MLH3
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背景
- Rabbit Anti-MLH3 Polyclonal Antibody,MLH3, DNA mismatch repair protein Mlh3, MutL protein homolog 3,MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.,DNA mismatch repair protein Mlh3
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分子量
- observerd band 164kDa
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基因ID
- 27030
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UniProt
- Q9UHC1
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途径
- Chromatin Binding
抗原
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