MAP3K14 抗体 (AA 90-170)
Our Local Distributor
北京 101111
Quick Overview for MAP3K14 抗体 (AA 90-170) (ABIN7229494)
抗原
See all MAP3K14 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 90-170
-
原理
- M3K14 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of M3K14 protein
-
纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
-
免疫原
- Synthesized peptide derived from part region of human M3K14 protein at AA range: 90-170
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))
-
别名
- M3K14
-
背景
- Rabbit Anti-M3K14 Polyclonal Antibody,Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, HsNIK, Serine/threonine-protein kinase NIK,MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. MAP3K14 is a Protein Coding gene. Diseases associated with MAP3K14 include Nik Deficiency. Among its related pathways are 4-1BB Pathway and RANK Signaling in Osteoclasts.,M3K14
-
分子量
- observerd band 104kDa
-
基因ID
- 9020
-
UniProt
- Q99558
-
途径
- NF-kappaB Signaling, TCR Signaling
抗原
-