MAP3K11 抗体 (pSer674)
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Quick Overview for MAP3K11 抗体 (pSer674) (ABIN7213356)
抗原
See all MAP3K11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer674
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原理
- MLK3 (phospho Ser674) Polyclonal Antibody
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特异性
- Phospho-MLK3 (S674) Polyclonal Antibody detects endogenous levels of MLK3 protein only when phosphorylated at S674.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human MLK3 Phospho-Ser674
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MAP3K11 (Mitogen-Activated Protein Kinase Kinase Kinase 11 (MAP3K11))
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别名
- MLK3
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背景
- Rabbit Anti-MLK3 (phospho Ser674) Polyclonal Antibody,MAP3K11, MLK3, PTK1, SPRK, Mitogen-activated protein kinase kinase kinase 11, Mixed lineage kinase 3, Src-homology 3 domain-containing proline-rich kinase,Mitogen-activated protein kinase 11 encoded by MAP3K11 is a member of the serine/threonine kinase family. Mitogen-activated protein kinase 11 contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42.,Mitogen-activated protein kinase kinase kinase 11
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基因ID
- 4296
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UniProt
- Q16584
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途径
- MAPK Pathway, Interferon-gamma Pathway
抗原
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