MCM6 抗体 (Internal Region)
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Quick Overview for MCM6 抗体 (Internal Region) (ABIN7218428)
抗原
See all MCM6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- MCM6 Polyclonal Antibody
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特异性
- MCM6 Polyclonal Antibody detects endogenous levels of MCM6 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human MCM6
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亚型
- IgG
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anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibody
MCM6 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyKD Validated MCM6 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 23GB2005 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 适用: 人 WB, IF, IHC (p), PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 228-368) antibodyMCM6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MCM6-2999 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 1-821) antibodyMCM6 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7D8 unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 589-605), (Middle Region) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, WB, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (AA 562-821) antibodyMCM6 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) (C-Term) antibodyMCM6 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 6 (MCM6) antibodyMCM6 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MCM6 (Minichromosome Maintenance Complex Component 6 (MCM6))
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别名
- MCM6
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背景
- Rabbit Anti-MCM6 Polyclonal Antibody,MCM6, DNA replication licensing factor MCM6, p105MCM,DNA replication licensing factor MCM6 encoded by MCM6 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. Single nucleotide polymorphisms in the intron regions of this gene are associated with differential transcriptional activation of the promoter of the neighboring lactase gene and, thereby, influence lactose intolerance in early adulthood.,DNA replication licensing factor MCM6
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分子量
- observerd band 90kDa
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基因ID
- 4175
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UniProt
- Q14566
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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