MCM3 抗体 (Internal Region)
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Quick Overview for MCM3 抗体 (Internal Region) (ABIN7217970)
抗原
See all MCM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- Rabbit Anti-MCM3 Polyclonal Antibody
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特异性
- MCM3 Polyclonal Antibody detects endogenous levels of MCM3 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from the Internal region of human MCM3
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亚型
- IgG
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anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibody
MCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4F7 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 699-808) antibodyMCM3 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3E1 unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 13-27), (N-Term) antibodyMCM3 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) (AA 1-295) antibodyMCM3 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 IHC 宿主: 小鼠 Monoclonal 503M unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyKD Validated MCM3 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2490 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 3 (MCM3) antibodyMCM3 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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别名
- MCM3
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背景
- MCM3, DNA replication licensing factor MCM3, DNA polymerase alpha holoenzyme-associated protein P1, P1-MCM3, RLF subunit beta, p102Minichromosome maintenance complex component 3 encoded by MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
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分子量
- 89kD
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基因ID
- 4172
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UniProt
- P25205
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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