MIB1 抗体 (AA 901-950)
Our Local Distributor
北京 101111
Quick Overview for MIB1 抗体 (AA 901-950) (ABIN7226942)
抗原
See all MIB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 901-950
-
原理
- Rabbit Anti-MIB1 Polyclonal Antibody
-
特异性
- The antibody detects endogenous MIB1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthetic peptide from human protein at AA range: 901-950
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300,WB 1:500-2000,ELISA 1:10000-20000,IF 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- MIB1 (Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB1))
-
别名
- MIB1
-
背景
- MIB1, DIP1, KIAA1323, ZZANK2MIB1 (mindbomb E3 ubiquitin protein ligase 1) encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
-
分子量
- 130kD
-
基因ID
- 57534
-
UniProt
- Q86YT6
-
途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
-