TIMP2 抗体 (AA 40-120)
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Quick Overview for TIMP2 抗体 (AA 40-120) (ABIN7217322)
抗原
See all TIMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 40-120
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原理
- TIMP-2 Polyclonal Antibody
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特异性
- TIMP-2 Polyclonal Antibody detects endogenous levels of TIMP-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human TIMP-2 at AA range: 40-120
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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别名
- TIMP-2
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背景
- Rabbit Anti-TIMP-2 Polyclonal Antibody,TIMP2, Metalloproteinase inhibitor 2, CSC-21K, Tissue inhibitor of metalloproteinases 2, TIMP-2,TIMP2 is a member of the TIMP gene family. Metalloproteinase inhibitor 2 encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the Metalloproteinase inhibitor 2 has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.,Metalloproteinase inhibitor 2
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分子量
- observerd band 25kDa
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基因ID
- 7077
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UniProt
- P16035
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途径
- cAMP Metabolic Process
抗原
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