MIA3 抗体 (AA 1110-1190)
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Quick Overview for MIA3 抗体 (AA 1110-1190) (ABIN7229662)
抗原
See all MIA3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1110-1190
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原理
- MIA3 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of MIA3 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human MIA3 protein at AA range: 1110-1190
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MIA3 (Melanoma Inhibitory Activity Family, Member 3 (MIA3))
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别名
- MIA3
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背景
- Rabbit Anti-MIA3 Polyclonal Antibody,Transport and Golgi organization protein 1 homolog, TANGO1, C219-reactive peptide, D320, Melanoma inhibitory activity protein 3,MIA3 (MIA Family Member 3, ER Export Factor) is a Protein Coding gene. Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. This protein is required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. It may participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1. It is also specifically required for the secretion of lipoproteins by participating in their export from the endoplasmic reticulum.,MIA3
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分子量
- observerd band 209kDa
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基因ID
- 375056
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UniProt
- Q5JRA6
抗原
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