MC1 Receptor 抗体 (AA 240-320)
Quick Overview for MC1 Receptor 抗体 (AA 240-320) (ABIN7222388)
抗原
See all MC1 Receptor (MC1R) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 240-320
-
原理
- MC1-R Polyclonal Antibody
-
特异性
- MC1-R Polyclonal Antibody detects endogenous levels of MC1-R protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
免疫原
- Synthesized peptide derived from the C-terminal region of human MC1-R at AA range: 240-320
-
亚型
- IgG
-
-
anti-Melanocortin 1 Receptor (MC1R) (AA 1-37) antibody
MC1R 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibodyMC1R 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (C-Term) antibodyMC1R 适用: 人 WB, IF, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 217-232) antibodyKO Validated MC1R 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) antibodyMC1R 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) antibodyKD Validated MC1R 适用: 人 WB 宿主: 兔 Monoclonal 25GB5955 unconjugated Recombinant Antibody
anti-Melanocortin 1 Receptor (MC1R) (Cytoplasmic Domain) antibodyMC1R 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Melanocortin 1 Receptor (MC1R) (AA 271-317) antibody (AbBy Fluor® 488)MC1R 适用: 人, 小鼠 WB, IF (cc), IF (p), FACS 宿主: 兔 Polyclonal AbBy Fluor® 488
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
-
说明
-
Primary Antibody
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- MC1 Receptor (MC1R) (Melanocortin 1 Receptor (MC1R))
-
别名
- MC1-R
-
背景
- Rabbit Anti-MC1-R Polyclonal Antibody,MC1R, MSHR, Melanocyte-stimulating hormone receptor, MSH-R, Melanocortin receptor 1, MC1-R,This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin exist: red pheomelanin and black eumelanin. Gene mutations that lead to a loss in function are associated with increased pheomelanin production, which leads to lighter skin and hair color. Eumelanin is photoprotective but pheomelanin may contribute to UV-induced skin damage by generating free radicals upon UV radiation. Binding of MSH to its receptor activates the receptor and stimulates eumelanin synthesis. This receptor is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer. Over 30 variant alleles have been identified which correlate with skin and hair color, providing evidence that MC1R(MSH) is an important component in determining normal human pigment variation.,Melanocyte-stimulating hormone receptor
-
分子量
- observerd band 35kDa
-
基因ID
- 4157
-
UniProt
- Q01726
-
途径
- cAMP Metabolic Process, Feeding Behaviour
抗原
-
