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MMP12 抗体 (C-Term)

This anti-MMP12 antibody is a 兔 多克隆 antibody detecting MMP12 in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7222510
发货至: 中国

Quick Overview for MMP12 抗体 (C-Term) (ABIN7222510)

抗原

See all MMP12 抗体
MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

适用

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宿主

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克隆类型

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多克隆

标记

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This MMP12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    原理

    MMP-12 Polyclonal Antibody

    特异性

    MMP-12 Polyclonal Antibody detects endogenous levels of MMP-12 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the C-terminal region of human MMP-12

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))

    别名

    MMP-12

    背景

    Rabbit Anti-MMP-12 Polyclonal Antibody,MMP12, HME, Macrophage metalloelastase, MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12,MMP12 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. MMP12 may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11.,Macrophage metalloelastase

    分子量

    observerd band 48kDa

    基因ID

    4321

    UniProt

    P39900
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