MMP12 抗体 (Cleaved-Gly106)
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北京 101111
Quick Overview for MMP12 抗体 (Cleaved-Gly106) (ABIN7212486)
抗原
See all MMP12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-140, Cleaved-Gly106
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原理
- Cleaved-MMP-12 (G106) Polyclonal Antibody
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特异性
- Cleaved-MMP-12 (G106) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-12 protein resulting from cleavage adjacent to G106.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human MMP-12 at AA range: 60-140
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亚型
- IgG
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anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 20-99) antibody
MMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 100-286) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 391-420), (C-Term) antibodyMMP12 适用: 人, 小鼠 WB, IHC (p), IF 宿主: 兔 Polyclonal RB2026 unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 290-469) antibodyMMP12 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 294-473) antibodyMMP12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 372-463) antibodyMMP12 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 1-470) antibodyMMP12 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 109-470) antibodyMMP12 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) antibodyMMP12 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 201-300) antibodyMMP12 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
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别名
- MMP-12
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背景
- Rabbit Anti-Cleaved-MMP-12 (G106) Polyclonal Antibody,MMP12, HME, Macrophage metalloelastase, MME, Macrophage elastase, ME, hME, Matrix metalloproteinase-12, MMP-12,MMP12 encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Matrix metallopeptidase 12 degrades soluble and insoluble elastin. MMP12 may play a role in aneurysm formation and mutations MMP12 are associated with lung function and chronic obstructive pulmonary disease (COPD). MMP12 is part of a cluster of MMP genes on chromosome 11.,Macrophage metalloelastase
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分子量
- observerd band 42kDa
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基因ID
- 4321
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UniProt
- P39900
抗原
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