JMJD2D 抗体 (AA 400-480)
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Quick Overview for JMJD2D 抗体 (AA 400-480) (ABIN7229270)
抗原
See all JMJD2D (KDM4D) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 400-480
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原理
- KDM4D Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of KDM4D protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human KDM4D protein at AA range: 400-480
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))
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别名
- KDM4D
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背景
- Rabbit Anti-KDM4D Polyclonal Antibody,Lysine-specific demethylase 4D, JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D,KDM4D (Lysine Demethylase 4D) is a Protein Coding gene. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include dioxygenase activity and histone demethylase activity (H3-K9 specific). An important paralog of this gene is KDM4F. Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36 nor H4 Lys-20. Demethylates both di- and trimethylated H3 Lys-9 residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,KDM4D
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分子量
- observerd band 57kDa
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基因ID
- 55693
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UniProt
- Q6B0I6
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途径
- Warburg Effect
抗原
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