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JMJD2D 抗体 (AA 400-480)

This 兔 多克隆 anti-JMJD2D antibody specifically detects JMJD2D in ELISA 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN7229270
发货至: 中国
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Quick Overview for JMJD2D 抗体 (AA 400-480) (ABIN7229270)

抗原

See all JMJD2D (KDM4D) 抗体
JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

适用

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宿主

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克隆类型

  • 36
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多克隆

标记

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This JMJD2D antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 抗原表位

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    AA 400-480

    原理

    KDM4D Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of KDM4D protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human KDM4D protein at AA range: 400-480

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    JMJD2D (KDM4D) (Lysine (K)-Specific Demethylase 4D (KDM4D))

    别名

    KDM4D

    背景

    Rabbit Anti-KDM4D Polyclonal Antibody,Lysine-specific demethylase 4D, JmjC domain-containing histone demethylation protein 3D, Jumonji domain-containing protein 2D,KDM4D (Lysine Demethylase 4D) is a Protein Coding gene. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include dioxygenase activity and histone demethylase activity (H3-K9 specific). An important paralog of this gene is KDM4F. Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36 nor H4 Lys-20. Demethylates both di- and trimethylated H3 Lys-9 residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,KDM4D

    分子量

    observerd band 57kDa

    基因ID

    55693

    UniProt

    Q6B0I6

    途径

    Warburg Effect
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