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LRP3 抗体 (AA 30-110)

This anti-LRP3 antibody is a 兔 多克隆 antibody detecting LRP3 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7222266
发货至: 中国

Quick Overview for LRP3 抗体 (AA 30-110) (ABIN7222266)

抗原

See all LRP3 抗体
LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))

适用

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  • 12
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 18
  • 2

克隆类型

  • 18
  • 2
多克隆

标记

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  • 1
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This LRP3 antibody is un-conjugated

应用范围

  • 12
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Western Blotting (WB), ELISA
  • 抗原表位

    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-110

    原理

    LRP3 Polyclonal Antibody

    特异性

    LRP3 Polyclonal Antibody detects endogenous levels of LRP3 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the N-terminal region of human LRP3 at AA range: 30-110

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))

    别名

    LRP3

    背景

    Rabbit Anti-LRP3 Polyclonal Antibody,LRP3, Low-density lipoprotein receptor-related protein 3, LRP-3, 105 kDa low-density lipoprotein receptor-related protein, hLRp105,NLRP3, also known as NALP3, CIAS1, PYPAF or Cryopyrin, is a cytosolic ~120 kDa member of the NLRP family of proteins expressed in leukocytes, especially neutrophils. As a component of the inflammasome, NLRP3 activates caspases 1 and 5. Defects in NLRP3 may cause FCAS1, CINCA, or Muckle-Wells autoinflammatory syndromes. Mouse NLRP3 contains an N-terminal Pyrin domain (aa 1-91) followed by a Nacht region (aa 216-532), and seven LRRs (aa 739-988). Within the sequence used as an immunogen, mouse NLRP3 shares 78 % and 93 % aa identity with human and rat NLRP3, respectively. Alternate splicing of mouse NLRP3 generates additional isoforms that lack either LRR2 and 3, LRR 6 and 7, or LRR4-9.,Low-density lipoprotein receptor-related protein 3

    分子量

    observerd band 80kDa

    基因ID

    4037

    UniProt

    O75074
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