LFNG 抗体 (AA 90-170)
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北京 101111
Quick Overview for LFNG 抗体 (AA 90-170) (ABIN7222196)
抗原
See all LFNG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 90-170
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原理
- Lunatic Fringe Polyclonal Antibody
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特异性
- Lunatic Fringe Polyclonal Antibody detects endogenous levels of Lunatic Fringe protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Lunatic Fringe at AA range: 90-170
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亚型
- IgG
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anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (AA 1-250) antibody
LFNG 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (AA 1-250) antibodyLFNG 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D10-3C11 unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (Internal Region) antibodyLFNG 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (AA 74-123) antibodyLFNG 适用: 人, 小鼠, 大鼠, 豚鼠, Hamster, 猴, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (AA 1-250) antibodyLFNG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F9 unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (AA 86-114) antibodyLFNG 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24078 unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (AA 93-122), (Middle Region) antibodyLFNG 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) antibodyLFNG 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) antibodyLFNG 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB6595 unconjugated Recombinant Antibody
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) (Internal Region) antibodyLFNG 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
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别名
- Lunatic Fringe
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背景
- Rabbit Anti-Lunatic Fringe Polyclonal Antibody,LFNG, Beta-1, 3-N-acetylglucosaminyltransferase lunatic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase,LFNG is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.,Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
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分子量
- observerd band 42kDa
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基因ID
- 3955
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UniProt
- Q8NES3
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途径
- Notch Signaling
抗原
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