LMTK2 抗体 (AA 620-700)
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Quick Overview for LMTK2 抗体 (AA 620-700) (ABIN7220554)
抗原
See all LMTK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 620-700
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原理
- KPI-2 Polyclonal Antibody
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特异性
- KPI-2 Polyclonal Antibody detects endogenous levels of KPI-2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human KPI-2 at AA range: 620-700
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- LMTK2 (Lemur tyrosine Kinase 2 (LMTK2))
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别名
- KPI-2
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背景
- Rabbit Anti-KPI-2 Polyclonal Antibody,LMTK2, AATYK2, BREK, KIAA1079, KPI2, LMR2, Serine/threonine-protein kinase LMTK2, Apoptosis-associated tyrosine kinase 2, Brain-enriched kinase, hBREK, CDK5/p35-regulated kinase, CPRK, Kinase/phosphatase/inhibitor 2, Lemur tyrosine kinase 2,The lemur tyrosine kinase 2 encoded by LMTK2 belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis.,serine threonine-protein kinase LMTK2
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分子量
- observerd band 164kDa
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基因ID
- 22853
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UniProt
- Q8IWU2
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途径
- RTK signaling, Neurotrophin Signaling Pathway
抗原
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