Krs-1/2 (pThr183) 抗体
The 兔 多克隆 anti-Krs-1/2 antibody is suitable to detect Krs-1/2 in samples from 人 和 小鼠. It has been validated for ELISA, WB, IHC 和 IF.
产品编号 ABIN7224532
发货至:
中国
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北京 101111
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Quick Overview for Krs-1/2 (pThr183) 抗体 (ABIN7224532)
抗原
Krs-1/2
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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抗原表位
- pThr183
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原理
- Rabbit Anti-Krs-1/2 (phospho Thr183) Polyclonal Antibody
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特异性
- Phospho-Krs-1/2 (T183) Polyclonal Antibody detects endogenous levels of Krs-1/2 protein only when phosphorylated at T183.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Krs-1/2 Phospho-Thr183
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亚型
- IgG
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anti-Krs-1/2 antibody
适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Krs-1/2 (pThr183) antibody适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Krs-1/2
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背景
- STK3, KRS1, MST2, Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1, STK4, KRS2, MST1, Serine/threonine-protein kinase 4, Mammalian STE20-like protThe protein encoded by STK4 (serine/threonine kinase 4) is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
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分子量
- 60kD
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基因ID
- 6789
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UniProt
- Q13188, Q13043
抗原
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