Krs-1/2 抗体
This 兔 多克隆 antibody specifically detects Krs-1/2 in ELISA, WB, IHC 和 IF. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7224530
发货至:
中国
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中国
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北京 101111
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Quick Overview for Krs-1/2 抗体 (ABIN7224530)
抗原
Krs-1/2
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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原理
- Rabbit Anti-Krs-1/2 Polyclonal Antibody
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特异性
- Krs-1/2 Polyclonal Antibody detects endogenous levels of Krs-1/2 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from human Krs-1/2 around the non-phosphorylation site of T183
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亚型
- IgG
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anti-Krs-1/2 antibody
适用: 人, 小鼠, 大鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Krs-1/2 (pThr183) antibody适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Krs-1/2
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背景
- STK3, KRS1, MST2, Serine/threonine-protein kinase 3, Mammalian STE20-like protein kinase 2, MST-2, STE20-like kinase MST2, Serine/threonine-protein kinase Krs-1, STK4, KRS2, MST1, Serine/threonine-protein kinase 4, Mammalian STE20-like protSTK3 (serine/threonine kinase 3) encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for STK3.
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分子量
- 56kD
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基因ID
- 6788, 6789
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UniProt
- Q13188, Q13043
抗原
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