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KISS1 抗体

This anti-KISS1 antibody is a 兔 多克隆 antibody detecting KISS1 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7229292
发货至: 中国
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北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KISS1 抗体 (ABIN7229292)

抗原

See all KISS1 抗体
KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

适用

  • 36
  • 16
  • 4
人, 小鼠

宿主

  • 35
  • 5

克隆类型

  • 35
  • 5
多克隆

标记

  • 29
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This KISS1 antibody is un-conjugated

应用范围

  • 22
  • 14
  • 13
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 原理

    KISS1 Polyclonal Antibody

    特异性

    The antibody detects endogenous levels of KISS1 protein

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

    免疫原

    Synthesized peptide derived from part region of human KISS1 protein

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))

    别名

    KISS1

    背景

    Rabbit Anti-KISS1 Polyclonal Antibody,Metastasis-suppressor KiSS-1, Kisspeptin-1,KISS1 gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues.,KISS1

    分子量

    observerd band 15kDa

    基因ID

    3814

    UniProt

    Q15726

    途径

    Positive Regulation of Peptide Hormone Secretion
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