Kallikrein 5 抗体
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北京 101111
Quick Overview for Kallikrein 5 抗体 (ABIN7229312)
抗原
See all Kallikrein 5 (KLK5) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Rabbit Anti-KLK5 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of KLK5 protein
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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免疫原
- Synthesized peptide derived from part region of human KLK5 protein
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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有效期
- 12 months
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- Kallikrein 5 (KLK5)
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别名
- KLK5
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背景
- Kallikrein-5, Kallikrein-like protein 2, KLK-L2, Stratum corneum tryptic enzymeKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. Kallikrein Related Peptidase 5 is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein.
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分子量
- 32kD
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基因ID
- 25818
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UniProt
- Q9Y337
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途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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