JAK2 抗体 (pTyr119)
Quick Overview for JAK2 抗体 (pTyr119) (ABIN7221940)
抗原
See all JAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr119
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原理
- JAK2 (phospho Tyr119) Polyclonal Antibody
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特异性
- Phospho-JAK2 (Y119) Polyclonal Antibody detects endogenous levels of JAK2 protein only when phosphorylated at Y119.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human JAK2 Phospho-Tyr119
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- JAK2 (Janus Kinase 2 (JAK2))
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别名
- JAK2
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背景
- Rabbit Anti-JAK2 (phospho Tyr119) Polyclonal Antibody,JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2,JAK2 product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.,Tyrosine-protein kinase JAK2
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分子量
- observerd band 130kDa
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基因ID
- 3717
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UniProt
- O60674
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途径
- JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
抗原
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