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JAK2 抗体 (pTyr570)

This anti-JAK2 antibody is a 兔 多克隆 antibody detecting JAK2 in WB, ELISA 和 IHC (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7221934
发货至: 中国

Quick Overview for JAK2 抗体 (pTyr570) (ABIN7221934)

抗原

See all JAK2 抗体
JAK2 (Janus Kinase 2 (JAK2))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This JAK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pTyr570

    原理

    JAK2 (phospho Tyr570) Polyclonal Antibody

    特异性

    Phospho-JAK2 (Y570) Polyclonal Antibody detects endogenous levels of JAK2 protein only when phosphorylated at Y570.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human JAK2 Phospho-Tyr570

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    JAK2 (Janus Kinase 2 (JAK2))

    别名

    JAK2

    背景

    Rabbit Anti-JAK2 (phospho Tyr570) Polyclonal Antibody,JAK2, Tyrosine-protein kinase JAK2, Janus kinase 2, JAK-2,JAK2 product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.,Tyrosine-protein kinase JAK2

    分子量

    observerd band 130kDa

    基因ID

    3717

    UniProt

    O60674

    途径

    JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
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