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IL-10 抗体 (Internal Region)

This anti-IL-10 antibody is a 兔 多克隆 antibody detecting IL-10 in WB, ELISA 和 IHC (p). Suitable for 人.
产品编号 ABIN7217826
发货至: 中国

Quick Overview for IL-10 抗体 (Internal Region) (ABIN7217826)

抗原

See all IL-10 (IL10) 抗体
IL-10 (IL10) (Interleukin 10 (IL10))

适用

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克隆类型

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多克隆

标记

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This IL-10 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Internal Region

    原理

    IL-10 Polyclonal Antibody

    特异性

    IL-10 Polyclonal Antibody detects endogenous levels of IL-10 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human IL-10

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    IL-10 (IL10) (Interleukin 10 (IL10))

    别名

    IL-10

    背景

    Rabbit Anti-IL-10 Polyclonal Antibody,IL10, Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF,Interleukin-10 encoded by IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.,Interleukin-10

    分子量

    observerd band 20kDa

    基因ID

    3586

    UniProt

    P22301

    途径

    Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints
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