IFI16 抗体 (AA 700-780)
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北京 101111
Quick Overview for IFI16 抗体 (AA 700-780) (ABIN7221668)
抗原
See all IFI16 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 700-780
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原理
- IFI-16 Polyclonal Antibody
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特异性
- IFI-16 Polyclonal Antibody detects endogenous levels of IFI-16 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human IFI-16 at AA range: 700-780
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
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别名
- IFI-16
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背景
- Rabbit Anti-IFI-16 Polyclonal Antibody,IFI16, IFNGIP1, Gamma-interferon-inducible protein 16, Ifi-16, Interferon-inducible myeloid differentiation transcriptional activator,IFI16 encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,Gamma-interferon-inducible protein 16
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分子量
- observerd band 88kDa
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基因ID
- 3428
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UniProt
- Q16666
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
抗原
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