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IFNAR1 抗体 (pTyr466)

This 兔 多克隆 anti-IFNAR1 antibody specifically detects IFNAR1 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7221686
发货至: 中国
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Quick Overview for IFNAR1 抗体 (pTyr466) (ABIN7221686)

抗原

See all IFNAR1 抗体
IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This IFNAR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    pTyr466

    原理

    IFN-α/βRα (phospho Tyr466) Polyclonal Antibody

    特异性

    Phospho-IFN-α/βRα (Y466) Polyclonal Antibody detects endogenous levels of IFN-α/βRα protein only when phosphorylated at Y466.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from human IFN-alpha/betaRalpha Phospho-Tyr466

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

    别名

    IFN-alpha/betaRalpha

    背景

    Rabbit Anti-IFN-α/βRα (phospho Tyr466) Polyclonal Antibody,IFNAR1, IFNAR, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1,Interferon alpha and beta receptor subunit 1 encoded by IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.,Interferon alpha

    分子量

    observerd band 63kDa

    基因ID

    3454

    UniProt

    P17181

    途径

    JAK/STAT Signaling, Hepatitis C
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