IFNAR1 抗体 (pTyr466)
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北京 101111
Quick Overview for IFNAR1 抗体 (pTyr466) (ABIN7221686)
抗原
See all IFNAR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr466
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原理
- IFN-α/βRα (phospho Tyr466) Polyclonal Antibody
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特异性
- Phospho-IFN-α/βRα (Y466) Polyclonal Antibody detects endogenous levels of IFN-α/βRα protein only when phosphorylated at Y466.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human IFN-alpha/betaRalpha Phospho-Tyr466
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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别名
- IFN-alpha/betaRalpha
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背景
- Rabbit Anti-IFN-α/βRα (phospho Tyr466) Polyclonal Antibody,IFNAR1, IFNAR, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1,Interferon alpha and beta receptor subunit 1 encoded by IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.,Interferon alpha
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分子量
- observerd band 63kDa
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基因ID
- 3454
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UniProt
- P17181
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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