IDE 抗体
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北京 101111
Quick Overview for IDE 抗体 (ABIN7211960)
抗原
See all IDE 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- IDE Monoclonal Antibody
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特异性
- The antibody detects endogenous IDE proteins.
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纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
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免疫原
- Synthetic Peptide
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亚型
- IgG1
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anti-Insulin-Degrading Enzyme (IDE) (AA 491-590) antibody
IDE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 753-973) antibodyIDE 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 1-250) antibodyIDE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyIDE 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Insulin-Degrading Enzyme (IDE) (Internal Region) antibodyVerified IDE 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (AA 920-1019) antibodyIDE 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) (N-Term) antibodyIDE 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Insulin-Degrading Enzyme (IDE) antibodyKD Validated IDE 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB6210 unconjugated Recombinant Antibody
anti-Insulin-Degrading Enzyme (IDE) (AA 501-800) antibodyIDE 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000), IF (1:100-1:200), IHC-P (1:200).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- IDE (Insulin-Degrading Enzyme (IDE))
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别名
- IDE
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背景
- Mouse Anti-IDE Monoclonal Antibody,IDE, Insulin-degrading enzyme, Abeta-degrading protease, Insulin protease, Insulinase, Insulysin,IDE encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of insulin degrading enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in IDE have not been shown to be causitive for these diseases. Insulin degrading enzyme localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.,Insulin-degrading enzyme
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分子量
- observerd band 118kDa
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基因ID
- 3416
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UniProt
- P14735
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途径
- SARS-CoV-2 Protein Interactome
抗原
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