GPR109B 抗体 (AA 270-350)
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北京 101111
Quick Overview for GPR109B 抗体 (AA 270-350) (ABIN7225678)
抗原
See all GPR109B (HCAR3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 270-350
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原理
- HM74 Polyclonal Antibody
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特异性
- HM74 Polyclonal Antibody detects endogenous levels of HM74 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the C-terminal region of human HM74 at AA range: 270-350
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亚型
- IgG
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anti-Hydroxycarboxylic Acid Receptor 3 (HCAR3) antibody
HCAR3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxycarboxylic Acid Receptor 3 (HCAR3) (Cytoplasmic Domain) antibodyHCAR3 适用: 人, 犬, Hamster IHC (p), IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxycarboxylic Acid Receptor 3 (HCAR3) (AA 1-387) antibodyHCAR3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxycarboxylic Acid Receptor 3 (HCAR3) (Extracellular Domain), (N-Term) antibodyHCAR3 适用: 人 IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- GPR109B (HCAR3) (Hydroxycarboxylic Acid Receptor 3 (HCAR3))
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别名
- HM74
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背景
- Rabbit Anti-HM74 Polyclonal Antibody,HCAR3, GPR109B, HCA3, HM74B, NIACR2, Hydroxycarboxylic acid receptor 3, G-protein coupled receptor 109B, G-protein coupled receptor HM74, G-protein coupled receptor HM74B, Niacin receptor 2, Nicotinic acid receptor 2, HCAR2, GPR109A, HCA2,HM74, also known as PUMAG or Puma-g, is a member of the G protein coupled receptor (GPCR) superfamily. In humans, HM74 is encoded by two different genes (GPR109A and GPR109B) that express two distinct proteins, namely HM74A and HM74B (also known as simply HM74), which are 96 % homologous. In mice and rats, only one gene (deisngnated Gpr109a) encodes the HM74 protein. HM74B is a Gi protein-coupled receptor that mediates the metabolic effects of nicotinic acid. Localizing to the cell membrane, HM74B is highly expressed in adipocytes, immune cells and spleen and, like all members of the GPCR superfamily, contains seven transmembrane domains. HM74B lacks the characteristic N-linked glycosylation sites that are present in other GPCR family members and also shows a more diverged amino acid sequence homology from most family members, implying different ligand specificity.,G-protein coupled receptor 109B
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分子量
- observerd band 45kDa
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基因ID
- 8843, 338442
抗原
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