HUS1 抗体 (AA 160-240)
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Quick Overview for HUS1 抗体 (AA 160-240) (ABIN7228986)
抗原
See all HUS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-240
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原理
- HUS1 Polyclonal Antibody
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特异性
- The antibody detects endogenous levels of HUS1 protein
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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免疫原
- Synthesized peptide derived from part region of human HUS1 protein at AA range: 160-240
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
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别名
- HUS1
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背景
- Rabbit Anti-HUS1 Polyclonal Antibody,Checkpoint protein HUS1, hHUS1,The protein encoded by HUS1 is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.,HUS1
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分子量
- observerd band 30kDa
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基因ID
- 3364
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UniProt
- O60921
抗原
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