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HUS1 抗体

HUS1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7261357
发货至: 中国
  • 抗原 See all HUS1 抗体
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    适用
    • 51
    • 28
    • 14
    人, 小鼠
    宿主
    • 62
    • 4
    克隆类型
    • 65
    • 1
    多克隆
    标记
    • 23
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HUS1 antibody is un-conjugated
    应用范围
    • 32
    • 27
    • 13
    • 13
    • 9
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human HUS1 (NP_004498.1).
    亚型
    IgG
    Top Product
    Discover our top product HUS1 Primary Antibody
  • 应用备注
    IF 1:50-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))
    别名
    HUS1 (HUS1 产品)
    别名
    hHUS1 antibody, mHus1 antibody, XHus1 antibody, hus1 antibody, HUS1 checkpoint clamp component antibody, checkpoint clamp complex protein Hus1 antibody, HUS1 checkpoint clamp component L homeolog antibody, HUS1 antibody, Hus1 antibody, hus1 antibody, hus1.L antibody
    背景
    The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.
    基因ID
    3364
    UniProt
    O60921
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