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HUNK 抗体 (AA 220-300)

This 兔 多克隆 anti-HUNK antibody specifically detects HUNK in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7221478
发货至: 中国
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Quick Overview for HUNK 抗体 (AA 220-300) (ABIN7221478)

抗原

HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))

适用

  • 42
  • 21
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 3

克隆类型

  • 48
  • 2
多克隆

标记

  • 20
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HUNK antibody is un-conjugated

应用范围

  • 40
  • 25
  • 13
  • 13
  • 12
  • 11
  • 3
  • 3
  • 2
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 8
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 220-300

    原理

    HUNK Polyclonal Antibody

    特异性

    HUNK Polyclonal Antibody detects endogenous levels of HUNK protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human HUNK at AA range: 220-300

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))

    别名

    HUNK

    背景

    Rabbit Anti-HUNK Polyclonal Antibody,HUNK, MAKV, Hormonally up-regulated neu tumor-associated kinase, B19, Serine/threonine-protein kinase MAK-V,The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50 % of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha and CAB39.,Hormonally up-regulated neu tumor-associated kinase

    分子量

    observerd band 75kDa

    基因ID

    30811

    UniProt

    P57058
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