HUNK 抗体 (AA 71-115)
-
- 抗原 See all HUNK products
- HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))
-
抗原表位
- AA 71-115
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This HUNK antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Serine/threonine-protein kinase MAK-V
- 亚型
- IgG
-
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (Kinase Domain) antibody
HUNK 适用: 人, 小鼠, 大鼠, 猴, Cow, 小鸡, 犬, Hamster, 马, 兔 IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (C-Term) antibodyHUNK 适用: 人, 猴, Cow ELISA, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 615-714) antibodyHUNK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (Internal Region) antibodyHUNK 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) antibodyHUNK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 615-714) antibodyHUNK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 615-714) antibodyHUNK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) antibodyHUNK 适用: 人, 小鼠, 猴, Cow, Chimpanzee, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hormonally Up-Regulated Neu-Associated Kinase (HUNK) (AA 659-690), (C-Term) antibodyHUNK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1268 unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- HUNK (Hormonally Up-Regulated Neu-Associated Kinase (HUNK))
- 别名
- Serine/threonine-protein kinase MAK-V (HUNK 产品)
- 别名
- HUNK antibody, TPT1P antibody, Bstk1 antibody, Mak-v antibody, RGD1565091 antibody, hormonally up-regulated Neu-associated kinase antibody, hormonally upregulated Neu-associated kinase antibody, HUNK antibody, Hunk antibody
- 背景
-
Synonyms: B19, Hormonally up-regulated neu tumor-associated kinase, Hormonally upregulated neu associated, Hormonally upregulated neu associated kinase, Hormonally upregulated neu tumor associated kinase, HUNK, HUNK_HUMAN, MAKV, Serine/threonine-protein kinase MAK-V.
Background: The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50 % of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter- and CAB39.
-
