HMG20B 抗体 (AA 10-90)
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北京 101111
Quick Overview for HMG20B 抗体 (AA 10-90) (ABIN7213838)
抗原
See all HMG20B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 10-90
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原理
- BRAF35 Polyclonal Antibody
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特异性
- BRAF35 Polyclonal Antibody detects endogenous levels of BRAF35 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the N-terminal region of human BRAF35 at AA range: 10-90
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亚型
- IgG
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anti-High Mobility Group 20B (HMG20B) (AA 1-109) antibody
HMG20B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 1-317) antibodyHMG20B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) antibodyHMG20B 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 1-317) antibodyHMG20B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 27-213) antibodyHMG20B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (AA 1-213) antibodyHMG20B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group 20B (HMG20B) (N-Term) antibodyHMG20B 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- HMG20B (High Mobility Group 20B (HMG20B))
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别名
- BRAF35
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背景
- Rabbit Anti-BRAF35 Polyclonal Antibody,HMG20B, BRAF35, HMGX2, HMGXB2, SMARCE1R, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, SMARCE1-related protein, BRCA2-associated factor 35, HMG box-containing protein 20B, HMG domain-,The breast cancer susceptibility gene (BRCA1) localizes to chromosome 17q. Mutations within this gene account for approximately 45 % of families with high incidence of breast cancer and at least 80 % of families with increased incidence of both early-onset breast cancer and ovarian cancer. A second breast cancer susceptibility gene, BRCA2, located on chromosome 13q12-13, also confers a high incidence of breast cancer, but unlike BRCA1, BRCA2 does not confer a substantially elevated risk of ovarian cancer. The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2, which associates with condensed chromatin during histone H3 phosphorylation. BRAF35 expression levels are highest in proliferating tissues and parallel BRCA2 expression patterns. The structure of BRAF35 includes a kinesin-like coiled coil domain and a nonspecific DNA binding HMG domain. The chromatin localization of BRAF35 and antibody microinjection studies indicate a role for the BRAF35/BRCA2 complex in cell cycle regulation.,SWI
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分子量
- observerd band 36kDa
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基因ID
- 10362
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UniProt
- Q9P0W2
抗原
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